{"id":3051,"date":"2023-12-08T09:02:45","date_gmt":"2023-12-08T14:02:45","guid":{"rendered":"https:\/\/newswz.com\/?p=3051"},"modified":"2023-12-08T09:04:37","modified_gmt":"2023-12-08T14:04:37","slug":"3%e7%a7%8d%e7%bb%b4%e7%94%9f%e7%b4%a0%e6%88%96%e8%87%b4%e8%82%ba%e7%99%8c%e6%88%96%e4%b9%b3%e8%85%ba%e7%99%8c%e5%a2%9e%e9%95%bf%ef%bc%9f%e8%bf%99%e4%b8%80%e7%b1%bb%e4%ba%ba%e5%ba%94%e9%81%bf%e5%85%8d","status":"publish","type":"post","link":"https:\/\/newswz.com\/?p=3051","title":{"rendered":"3\u79cd\u7ef4\u751f\u7d20\u6216\u81f4\u80ba\u764c\u6216\u4e73\u817a\u764c\u589e\u957f\uff1f\u8fd9\u4e00\u7c7b\u4eba\u5e94\u907f\u514d\u670d\u7528"},"content":{"rendered":"\n<p>\u6587\u7ae0\u6765\u6e90:\u00a0CC\u60c5\u62a5\u5c40\u00a0&#8211; 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Metabolism\uff09\u671f\u520a\u4e0a\u7684\u4e00\u7bc7\u7814\u7a76\u6587\u7ae0\uff0c\u8ba4\u4e3a\uff1a\u201c\u9ad8\u8868\u8fbe\u7684\u764c\u75c7\u9a71\u52a8\u57fa\u56e0MYC\u7684\u4e73\u817a\u80bf\u7624\u7ec6\u80de\u4e25\u91cd\u4f9d\u8d56\u7ef4\u751f\u7d20B5\uff0c\u8fdb\u884c\u7ec6\u80de\u7684\u751f\u957f\u548c\u5b58\u6d3b\uff1b\u76f8\u53cd\uff0c\u996e\u98df\u9650\u5236\u7ef4\u751f\u7d20B5\u5219\u4f1a\u9006\u8f6cMYC\u4ecb\u5bfc\u7684\u4ee3\u8c22\u53d8\u5316\uff0c\u963b\u788d\u80bf\u7624\u751f\u957f\u3002\u201d<strong>\u6362\u53e5\u8bdd\u8bf4\uff0c\u7ef4\u751f\u7d20B5\u662f\u5bfc\u81f4\u4e73\u817a\u764c\u7ec6\u80de\u5927\u91cf\u5feb\u901f\u589e\u6b96\u7684\u5e55\u540e\u63a8\u624b\u3002\u800c\u5982\u679c\u51cf\u5c11\u670d\u7528\uff0c\u5219\u53ef\u80fd\u4f1a\u53d7\u76ca\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/d.ifengimg.com\/w1080_h507_q90_webp\/x0.ifengimg.com\/ucms\/2023_49\/5534FE2ECCBEA5A7B586FE752B34479DB02D9AB3_size311_w1080_h507.png\" alt=\"\"\/><\/figure>\n\n\n\n<p><strong>\u7ef4\u751f\u7d20B5\u53c8\u53eb\u6cdb\u9178\uff0c\u8bb8\u591a\u5973\u6027\u670d\u7528\u5b83\u6765\u51cf\u5c11\u75e4\u75ae\uff0c<\/strong>\u00a0\u56e0\u4e3a\u5b83\u53ef\u4ee5\u5206\u89e3\u7518\u6cb9\u4e09\u8102\u548c\u80c6\u56fa\u9187\u3002\u540c\u65f6\u5b83\u8fd8\u53ef\u4ee5\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\uff0c\u5728\u751f\u6d3b\u4e2d\u51e0\u4e4e\u65e0\u5904\u4e0d\u5728\u3002<strong>\u8fd9\u6837\u4e00\u79cd\u666e\u901a\u7684\u7ef4\u751f\u7d20\u7247\uff0c\u5c45\u7136\u53ef\u4ee5\u4fc3\u8fdb\u4e73\u817a\u764c\u7ec6\u80de\u5927\u91cf\u5feb\u901f\u589e\u6b96\uff0c\u5f15\u8d77\u4e86\u4eba\u4eec\u7684\u6050\u614c\u3002<\/strong><\/p>\n\n\n\n<p>11\u6708\u4e2d\u65ec\uff0c\u53d1\u8868\u4e8e\u300a\u81ea\u7136\u00b7\u65b0\u9648\u4ee3\u8c22\u300b\uff08Nature Metabolism\uff09\u671f\u520a\u4e0a\u7684\u4e00\u7bc7\u7814\u7a76\u6587\u7ae0\uff0c\u8ba4\u4e3a\uff1a\u201c\u9ad8\u8868\u8fbe\u7684\u764c\u75c7\u9a71\u52a8\u57fa\u56e0MYC\u7684\u4e73\u817a\u80bf\u7624\u7ec6\u80de\u4e25\u91cd\u4f9d\u8d56\u7ef4\u751f\u7d20B5\uff0c\u8fdb\u884c\u7ec6\u80de\u7684\u751f\u957f\u548c\u5b58\u6d3b\uff1b\u76f8\u53cd\uff0c\u996e\u98df\u9650\u5236\u7ef4\u751f\u7d20B5\u5219\u4f1a\u9006\u8f6cMYC\u4ecb\u5bfc\u7684\u4ee3\u8c22\u53d8\u5316\uff0c\u963b\u788d\u80bf\u7624\u751f\u957f\u3002\u201d<strong>\u6362\u53e5\u8bdd\u8bf4\uff0c\u7ef4\u751f\u7d20B5\u662f\u5bfc\u81f4\u4e73\u817a\u764c\u7ec6\u80de\u5927\u91cf\u5feb\u901f\u589e\u6b96\u7684\u5e55\u540e\u63a8\u624b\u3002\u800c\u5982\u679c\u51cf\u5c11\u670d\u7528\uff0c\u5219\u53ef\u80fd\u4f1a\u53d7\u76ca\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/d.ifengimg.com\/w1080_h507_q90_webp\/x0.ifengimg.com\/ucms\/2023_49\/5534FE2ECCBEA5A7B586FE752B34479DB02D9AB3_size311_w1080_h507.png\" alt=\"\"\/><\/figure>\n\n\n\n<p><strong>\u7ef4\u751f\u7d20B5\u53c8\u53eb\u6cdb\u9178\uff0c\u8bb8\u591a\u5973\u6027\u670d\u7528\u5b83\u6765\u51cf\u5c11\u75e4\u75ae\uff0c<\/strong>&nbsp;\u56e0\u4e3a\u5b83\u53ef\u4ee5\u5206\u89e3\u7518\u6cb9\u4e09\u8102\u548c\u80c6\u56fa\u9187\u3002\u540c\u65f6\u5b83\u8fd8\u53ef\u4ee5\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\uff0c\u5728\u751f\u6d3b\u4e2d\u51e0\u4e4e\u65e0\u5904\u4e0d\u5728\u3002<strong>\u8fd9\u6837\u4e00\u79cd\u666e\u901a\u7684\u7ef4\u751f\u7d20\u7247\uff0c\u5c45\u7136\u53ef\u4ee5\u4fc3\u8fdb\u4e73\u817a\u764c\u7ec6\u80de\u5927\u91cf\u5feb\u901f\u589e\u6b96\uff0c\u5f15\u8d77\u4e86\u4eba\u4eec\u7684\u6050\u614c\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"671\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/8221C174C0300CC8277F103F0EF0A218B7C8D17E_size604_w1080_h708-1-1024x671.webp\" alt=\"\" class=\"wp-image-3054\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/8221C174C0300CC8277F103F0EF0A218B7C8D17E_size604_w1080_h708-1-1024x671.webp 1024w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/8221C174C0300CC8277F103F0EF0A218B7C8D17E_size604_w1080_h708-1-300x197.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/8221C174C0300CC8277F103F0EF0A218B7C8D17E_size604_w1080_h708-1-768x503.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/8221C174C0300CC8277F103F0EF0A218B7C8D17E_size604_w1080_h708-1-585x384.webp 585w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/8221C174C0300CC8277F103F0EF0A218B7C8D17E_size604_w1080_h708-1.webp 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>\u4f46\u4ee4\u4eba\u611f\u5230\u9707\u60ca\u7684\u662f\uff0c\u4f3c\u4e4e\u5e76\u4e0d\u4ec5\u4ec5\u53ea\u6709B5\u53ef\u4ee5\u81f4\u764c\uff0c<\/strong>\u00a0\u4eca\u5e748\u6708\u5e95\uff0c\u53d1\u8868\u5728\u300a\u4e34\u5e8a\u7814\u7a76\u6742\u5fd7\u300b\u7684\u6587\u7ae0\u79f0\uff0c<strong>\u4e00\u9879\u9488\u5bf9\u8001\u9f20\u7684\u7814\u7a76\u8868\u660e\uff0c\u670d\u7528\u7ef4\u751f\u7d20C\u548c\u7ef4\u751f\u7d20E\u7b49\u6297\u6c27\u5316\u5242\u8865\u5145\u5242\uff0c\u53ef\u80fd\u523a\u6fc0\u80bf\u7624\u5185\u8840\u7ba1\u7684\u5f62\u6210\uff0c\u4ece\u800c\u5bfc\u81f4\u80ba\u764c\u53d8\u5927\u548c\u6269\u6563\uff0c\u751f\u957f\u66f4\u5feb\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"720\" height=\"720\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/86AB5969565649995B3E62B020222CE301F6B826_size165_w720_h720.webp\" alt=\"\" class=\"wp-image-3055\" style=\"width:780px;height:auto\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/86AB5969565649995B3E62B020222CE301F6B826_size165_w720_h720.webp 720w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/86AB5969565649995B3E62B020222CE301F6B826_size165_w720_h720-300x300.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/86AB5969565649995B3E62B020222CE301F6B826_size165_w720_h720-150x150.webp 150w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/86AB5969565649995B3E62B020222CE301F6B826_size165_w720_h720-585x585.webp 585w\" sizes=\"(max-width: 720px) 100vw, 720px\" 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src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/137AA299373DAC25DF758A0B4BDBA6866AFD520A_size898_w1080_h607-1024x576.webp\" alt=\"\" class=\"wp-image-3056\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/137AA299373DAC25DF758A0B4BDBA6866AFD520A_size898_w1080_h607-1024x576.webp 1024w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/137AA299373DAC25DF758A0B4BDBA6866AFD520A_size898_w1080_h607-300x169.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/137AA299373DAC25DF758A0B4BDBA6866AFD520A_size898_w1080_h607-768x432.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/137AA299373DAC25DF758A0B4BDBA6866AFD520A_size898_w1080_h607-585x329.webp 585w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/137AA299373DAC25DF758A0B4BDBA6866AFD520A_size898_w1080_h607.webp 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>\u7ef4\u751f\u7d20B5\u5728\u5c0f\u9f20\u8eab\u4e0a\u53ef\u8bf1\u53d1\u4e73\u817a\u764c\u589e\u957f\uff0c\u662f\u5426\u610f\u5473\u7740\u7ef4\u751f\u7d20B5\u4f1a\u81f4\u764c\u5462\uff1f<\/strong><\/p>\n\n\n\n<p>\u6211\u4eec\u5148\u6765\u770b\u770b\u5173\u4e8e\u7ef4\u751f\u7d20B5\u662f\u5982\u4f55\u5bfc\u81f4\u4e73\u817a\u764c\u5feb\u901f\u589e\u6b96\u7684\u3002<\/p>\n\n\n\n<p>\u8fd9\u7bc7\u7814\u7a76\u662f\u5f17\u6717\u897f\u65af\u00b7\u514b\u91cc\u514b\u7814\u7a76\u6240\uff08 The Francis Crick Institute \uff09\u7b49\u5355\u4f4d\u7684\u8054\u5408\u7814\u7a76\u56e2\u961f\uff0c\u5728 Nature Metabolism \u53d1\u8868\u7684\u9898\u4e3a \u201cVitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer\u201d\u7684\u6587\u7ae0\u3002<strong>\u5176\u5927\u610f\u662f\uff0c\u7528\u6237\u5982\u679c\u8fc7\u591a\u670d\u7528\u901a\u5e38\u4e0e\u65b0\u9648\u4ee3\u8c22\u529f\u80fd\u6709\u5173\u7684\u7ef4\u751f\u7d20B5\uff0c\u53ef\u80fd\u4f1a\u8bf1\u53d1\u67d0\u4e9b\u7c7b\u578b\uff08\u4e73\u817a\u764c\uff09\u764c\u7ec6\u80de\u80bf\u7624\u3002<\/strong><\/p>\n\n\n\n<p>\u7ef4\u751f\u7d20B5\uff0c\u53c8\u79f0\u6cdb\u9178\uff0c\u8be5\u5355\u8bcd\u6765\u6e90\u4e8e\u5e0c\u814a\u8bed\u201c\u65e0\u5904\u4e0d\u5728\u7684\u9178\u7c7b\u7269\u8d28\u201d\uff0c\u5728\u81ea\u7136\u754c\u7684\u5206\u5e03\u6781\u5176\u5e7f\u6cdb\u3002\u6cdb\u9178\u53c2\u4e0e\u4f53\u5185\u591a\u79cd\u4ee3\u8c22\uff0c\u4fc3\u8fdb\u7cd6\u3001\u8102\u80aa\u3001\u6c28\u57fa\u9178\u4e2d\u7684\u4e59\u9178\u5206\u89e3\uff0c\u540c\u65f6\u4e5f\u662f\u591a\u9176\u590d\u5408\u7269\u8102\u80aa\u9178\u5408\u9176\u7684\u7ec4\u6210\u6210\u5206\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u56e2\u961f\u4f7f\u7528\u4e24\u79cd\u4e0d\u540c\u7c7b\u578b\u8868\u8fbe\u4eba\u7c7b\u81f4\u764c\u57fa\u56e0MYC\u7684\u7ec6\u80de\u57f9\u517b\u80bf\u7624\uff0c\u5e76\u5c06\u4eba\u7c7b\u4e73\u817a\u764c\u80bf\u7624\u7ec4\u7ec7\uff08\u542b\u6709\u9ad8\u8868\u8fbe MYC\u548c\u4f4e\u8868\u8fbe MYC\u7684\u6df7\u5408\u4f53\uff09\u79fb\u690d\u5230\u5c0f\u9f20\u4f53\u5185\u3002\u800c\u540e\u53d1\u73b0\uff0cMYC\u589e\u52a0\u4e86\u591a\u7ef4\u751f\u7d20\u8f6c\u8fd0\u86cb\u767dSLC5A6\u7684\u6570\u91cf\uff0c\u8fd9\u4f7f\u5f97\u66f4\u591a\u7684\u7ef4\u751f\u7d20B5\u8fdb\u5165\u7ec6\u80de\u5185\u3002\u5f53\u7814\u7a76\u56e2\u961f\u4f7f\u7ec6\u80de\u4ea7\u751f\u66f4\u591a\u7684SLC5A6\u65f6\uff0c\u66f4\u591a\u7684\u7ef4\u751f\u7d20B5\u8fdb\u5165\u7ec6\u80de\uff0c\u5373\u4f7f\u662f\u5728MYC\u4f4e\u8868\u8fbe\u7684\u7ec6\u80de\u4e2d\uff0c\u4e5f\u8ba9\u8fd9\u4e9b\u7ec6\u80de\u66f4\u5feb\u5730\u751f\u957f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"476\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/6F0D179B7CE488E368E7BF0E1B8745D7E194A186_size357_w1080_h502-1024x476.webp\" alt=\"\" class=\"wp-image-3057\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/6F0D179B7CE488E368E7BF0E1B8745D7E194A186_size357_w1080_h502-1024x476.webp 1024w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/6F0D179B7CE488E368E7BF0E1B8745D7E194A186_size357_w1080_h502-300x139.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/6F0D179B7CE488E368E7BF0E1B8745D7E194A186_size357_w1080_h502-768x357.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/6F0D179B7CE488E368E7BF0E1B8745D7E194A186_size357_w1080_h502-585x272.webp 585w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/6F0D179B7CE488E368E7BF0E1B8745D7E194A186_size357_w1080_h502.webp 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7814\u7a76\u56e2\u961f\u7528\u7f3a\u4e4f\u7ef4\u751f\u7d20B5\u7684\u996e\u98df\u5582\u517b\u5c0f\u9f20\uff0c\u7ed3\u679c\u663e\u793a\uff0cMYC\u4f4e\u8868\u8fbe\u548cMYC\u9ad8\u8868\u8fbe\u7684\u6df7\u5408\u80bf\u7624\uff0c\u6bd4\u90a3\u4e9b\u7528\u6807\u51c6\u996e\u98df\u5582\u517b\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u751f\u957f\u5f97\u66f4\u6162\u3002\u5f53\u4eba\u7c7b\u4e73\u817a\u764c\u7ec4\u7ec7\u88ab\u79fb\u690d\u5230\u5c0f\u9f20\u8eab\u4e0a\u65f6\uff0c\u4e5f\u89c2\u5bdf\u5230\u4e86\u540c\u6837\u7684\u60c5\u51b5\u3002\u6700\u7ec8\u5173\u8054\u6027\u5206\u6790\u663e\u793a\uff0c\u7ef4\u751f\u7d20B5\u4e0e\u4e73\u817a\u80bf\u7624\u4e2d\u7684MYC\u6c34\u5e73\u5b58\u5728\u6700\u5f3a\u7684\u76f8\u5173\u6027\uff0c\u5176\u5316\u5b66\u7ed3\u6784\u901a\u8fc7\u5316\u5b66\u6807\u51c6\u548c\u80bf\u7624\u7ec4\u7ec7\u8fdb\u884c\u4e32\u8054\u8d28\u8c31\u7cfb\u7edf\u786e\u8ba4\u5f97\u5230\u3002<\/p>\n\n\n\n<p><strong>\u7b80\u5355\u6765\u8bf4\uff0c\u5c31\u662f\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c\u81f4\u764c\u57fa\u56e0MYC\u7684\u4e73\u817a\u80bf\u7624\u7ec6\u80de\u751f\u957f\u548c\u5b58\u6d3b\u4e25\u91cd\u4f9d\u8d56\u7ef4\u751f\u7d20B5\uff0c\u800c\u996e\u98df\u4e2d\u9650\u5236\u7ef4\u751f\u7d20B5\u5219\u4f1a\u9006\u8f6cMYC\u4ecb\u5bfc\u7684\u4ee3\u8c22\u53d8\u5316\uff0c\u963b\u788d\u80bf\u7624\u751f\u957f\uff0c\u5c06\u6765\u6216\u8bb8\u53ef\u7528\u4e8e\u80bf\u7624\u6cbb\u7597\u4e2d\u3002<\/strong><\/p>\n\n\n\n<p><strong>\u90a3\u4e48\u8fd9\u662f\u4e0d\u662f\u610f\u5473\u7740\u7ef4\u751f\u7d20B5\u4f1a\u81f4\u764c\u5462\uff1f<\/strong><\/p>\n\n\n\n<p>2022\u5e741\u6708\u53d1\u8868\u4e8e\u300a\u7ec6\u80de\u00b7\u65b0\u9648\u4ee3\u8c22\u300b\uff08Cell Metabolism\uff09\u4e0a\u7684\u4e00\u9879\u7814\u7a76\u62a5\u544a\u79f0\uff0c\u7ef4\u751f\u7d20B5\u662f\u4e00\u79cd\u80fd\u591f\u523a\u6fc0\u4eba\u4f53\u6297\u764c\u514d\u75ab\u76d1\u63a7\u673a\u5236\u7684B\u65cf\u7ef4\u751f\u7d20\u3002\u5728\u4e00\u5c0f\u7fa4\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u4e2d\uff0c\u7ef4\u751f\u7d20B5\u7684\u8840\u6db2\u542b\u91cf\u4e0ePD-1\u9776\u5411\u514d\u75ab\u7597\u6cd5\u7684\u53cd\u5e94\u5448\u6b63\u76f8\u5173\uff0c\u540c\u65f6\u5728\u5c0f\u9f20\u5b9e\u9a8c\u4e2d\uff0c\u8865\u5145\u7ef4\u751f\u7d20 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\u201c\u7ef4\u751f\u7d20B5 \u662f\u6b63\u5e38\u8eab\u4f53\u529f\u80fd\u6240\u5fc5\u9700\u7684\uff0c\u8eab\u4f53\u5904\u4e8e\u81ea\u7136\u5e73\u8861\u7684\u72b6\u6001\u4e2d\uff0c\u8fc7\u591a\u5730\u670d\u7528\u7ef4\u751f\u7d20B5\uff0c\u53ef\u80fd\u4f1a\u4ea7\u751f\u6bd2\u526f\u4f5c\u7528\u3002 \u201d\u00a0<strong>\u5176\u4e2d\u7684\u5173\u952e\u8bcd\u662f\uff1a\u8fc7\u591a\u3002\u800c\u8bb8\u591a\u5173\u4e8e\u7ef4\u751f\u7d20\u53ef\u80fd\u81f4\u764c\u7684\u8868\u8ff0\uff0c\u90fd\u7ed5\u4e0d\u5f00\u8fd9\u4e2a\u8bcd\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"880\" height=\"720\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/7352278D1A82556EF7900EB459FE2541D2BC1566_size755_w880_h720.webp\" alt=\"\" class=\"wp-image-3058\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/7352278D1A82556EF7900EB459FE2541D2BC1566_size755_w880_h720.webp 880w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/7352278D1A82556EF7900EB459FE2541D2BC1566_size755_w880_h720-300x245.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/7352278D1A82556EF7900EB459FE2541D2BC1566_size755_w880_h720-768x628.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/7352278D1A82556EF7900EB459FE2541D2BC1566_size755_w880_h720-585x479.webp 585w\" sizes=\"(max-width: 880px) 100vw, 880px\" \/><\/figure>\n\n\n\n<p><strong>\u7ef4C\u548c\u7ef4E\u4f1a\u4f7f\u80ba\u764c\u751f\u957f\u66f4\u5feb\uff1f\u7ef4\u751f\u7d20E\u540c\u65f6\u8fd8\u4f1a\u5bfc\u81f4\u524d\u5217\u817a\u764c\u98ce\u9669\u589e\u52a0\uff1f<\/strong><\/p>\n\n\n\n<p><strong>\u7ef4C\u548cE\u90fd\u662f\u4eba\u4eec\u89e6\u624b\u53ef\u53ca\u7684\u65e5\u5e38\u6240\u89c1\u7684\u7ef4\u751f\u7d20\u3002\u4f46\u5173\u4e8e\u8fd9\u4e24\u79cd\u7ef4\u751f\u7d20\u5728\u4e0d\u540c\u7684\u764c\u75c7\u4e2d\u7684\u7814\u7a76\uff0c\u5219\u66f4\u4e3a\u5e7f\u6cdb\u3002<\/strong><\/p>\n\n\n\n<p>\u4eca\u5e748\u670831\u65e5\uff0c\u745e\u5178\u5361\u7f57\u6797\u65af\u5361\u5b66\u9662\u548c\u90d1\u5dde\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u7b49\u591a\u5bb6\u5408\u4f5c\u5355\u4f4d\u8054\u5408\u53d1\u8868\u4e8e\u300a\u4e34\u5e8a\u7814\u7a76\u6742\u5fd7\u300b\u7684\u6587\u7ae0\u53d1\u73b0\uff0c\u8865\u5145\u7ef4\u751f\u7d20C\u548cE\u7b49\u6297\u6c27\u5316\u5242\uff0c\u53ef\u80fd\u4f1a\u589e\u52a0\u80ba\u764c\u80bf\u7624\u5185\u8840\u7ba1\u7684\u5f62\u6210\uff0c\u4fc3\u4f7f\u80ba\u764c\u6076\u5316\u5e76\u6269\u6563\u3002<\/p>\n\n\n\n<p>\u5361\u7f57\u7433\u65af\u5361\u5b66\u9662\u9a6c\u4e01\u00b7\u535a\u683c\u56e2\u961f\u6b64\u524d\u53d1\u73b0\uff0c\u8865\u5145\u6297\u6c27\u5316\u5242\u7ef4\u751f\u7d20E\u548cn-\u4e59\u9170\u534a\u80f1\u6c28\u9178\u4f1a\u5bfc\u81f4\u80ba\u764c\u5728\u5c0f\u9f20\u4f53\u5185\u6269\u6563\u3002\u4e3a\u66f4\u597d\u5730\u7406\u89e3\u8fd9\u79cd\u60c5\u51b5\u662f\u5982\u4f55\u53d1\u751f\u7684\uff0c\u56e2\u961f\u7814\u7a76\u4e86\u7f79\u60a3\u80ba\u764c\u7684\u5c0f\u9f20\u548c\u690d\u5165\u4e86\u4eba\u7c7b\u764c\u75c7\u7ec6\u80de\u7684\u5c0f\u9f20\u3002\u4ed6\u4eec\u5728\u5c0f\u9f20\u7684\u996e\u7528\u6c34\u4e2d\u52a0\u5165\u4e86\u52a8\u7269\u81ea\u7136\u4ea7\u751f\u7684\u7ef4\u751f\u7d20C\uff0c\u4ee5\u53ca\u4ece\u996e\u98df\u4e2d\u83b7\u5f97\u7684\u7ef4\u751f\u7d20E\u548cn-\u4e59\u9170\u534a\u80f1\u6c28\u9178\u3002<\/p>\n\n\n\n<p>\u968f\u7740\u8865\u5145\u5242\u7684\u5242\u91cf\u8d8a\u6765\u8d8a\u5927\uff0c\u5c0f\u9f20\u4f53\u5185\u7684\u6297\u6c27\u5316\u5242\u6c34\u5e73\u9010\u6e10\u8d85\u8fc7\u5fc5\u8981\u7684\u6c34\u5e73\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c\u7ed9\u4e88\u5c0f\u9f20\u7684\u6297\u6c27\u5316\u5242\u5242\u91cf\u8d8a\u9ad8\uff0c\u5176\u80bf\u7624\u5185\u8840\u7ba1\u5f62\u6210\u7684\u901f\u7387\u5c31\u8d8a\u5feb\u3002<\/strong>\u00a0\u5bf9\u60a3\u6709\u9f20\u7279\u5f02\u6027\u80ba\u764c\u7684\u5c0f\u9f20\u548c\u88ab\u690d\u5165\u4eba\u7c7b\u764c\u7ec6\u80de\u7684\u5c0f\u9f20\u6765\u8bf4\uff0c\u90fd\u662f\u5982\u6b64\u3002<strong>\u8fd9\u9879\u7814\u7a76\u8ba4\u4e3a\uff0c\u8840\u7ba1\u751f\u957f\u52a0\u5feb\u53ef\u80fd\u4f1a\u5bfc\u81f4\u80ba\u764c\u7684\u751f\u957f\u548c\u6269\u6563\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"720\" height=\"945\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/FE456E9A43C769CDE6BF08E2F3B872C59DAA44F2_size251_w720_h945.webp\" alt=\"\" class=\"wp-image-3059\" style=\"width:780px;height:auto\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/FE456E9A43C769CDE6BF08E2F3B872C59DAA44F2_size251_w720_h945.webp 720w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/FE456E9A43C769CDE6BF08E2F3B872C59DAA44F2_size251_w720_h945-229x300.webp 229w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/FE456E9A43C769CDE6BF08E2F3B872C59DAA44F2_size251_w720_h945-585x768.webp 585w\" sizes=\"(max-width: 720px) 100vw, 720px\" \/><\/figure>\n\n\n\n<p>\u56e2\u961f\u8fd8\u7814\u7a76\u4e86\u4eba\u7c7b\u548c\u5c0f\u9f20\u7684\u764c\u75c7\u80bf\u7624\u7c7b\u5668\u5b98\u3002\u5728\u5c06\u8fd9\u4e9b\u7c7b\u5668\u5b98\u66b4\u9732\u4e8e\u9ad8\u5242\u91cf\u76843\u79cd\u6297\u6c27\u5316\u5242\u540e\uff0c\u4ed6\u4eec\u53d1\u73b0\uff0c\u8fd9\u4e9b\u6297\u6c27\u5316\u5242\u4e2d\u548c\u4e86\u7c7b\u5668\u5b98\u4e2d\u6240\u8c13\u7684\u6c27\u81ea\u7531\u57fa\u3002\u5728\u4e4b\u524d\u7684\u7814\u7a76\u4e2d\uff0c\u535a\u683c\u56e2\u961f\u8ba4\u4e3a\uff0c\u5c0f\u9f20\u5728\u8865\u5145\u7ef4\u751f\u7d20E\u548cn-\u4e59\u9170\u534a\u80f1\u6c28\u9178\u540e\uff0cBACH1\u86cb\u767d\u4f1a\u4fc3\u8fdb\u80ba\u764c\u80bf\u7624\u7684\u751f\u957f\u3002\u6700\u65b0\u7814\u7a76\u8868\u660e\uff0c\u5f53\u6c27\u81ea\u7531\u57fa\u6c34\u5e73\u4e0b\u964d\u65f6\uff0cBACH1\u88ab\u6fc0\u6d3b\uff0c\u8bf1\u5bfc\u8840\u7ba1\u5f62\u6210\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u4eba\u5458\u8868\u793a\uff0c\u8fd9\u4e9b\u53d1\u73b0\u53ef\u80fd\u4f1a\u4e3a\u6cbb\u7597\u67d0\u4e9b\u764c\u75c7\u5f00\u8f9f\u65b0\u9014\u5f84\u3002\u8840\u7ba1\u751f\u957f\u6291\u5236\u5242\u5e7f\u6cdb\u7528\u4e8e\u764c\u75c7\u6cbb\u7597\uff0c\u4f46\u53ef\u80fd\u4f1a\u4ea7\u751f\u8840\u6813\u7b49\u4e25\u91cd\u7684\u526f\u4f5c\u7528\u3002\u4e0d\u8fc7\uff0c\u5b83\u4eec\u53ef\u80fd\u5bf9\u80bf\u7624\u5185BACH1\u6c34\u5e73\u8f83\u9ad8\u7684\u4eba\u66f4\u6709\u6548\u3002\u867d\u7136\u4e0a\u8ff0\u5b9e\u9a8c\u90fd\u6d89\u53ca\u80ba\u764c\uff0c\u4f46\u4ed6\u4eec\u53d1\u73b0\uff0c\u4e0a\u8ff0\u60c5\u51b5\u4e5f\u9002\u5408\u80be\u764c\u548c\u4e73\u817a\u764c\u3002<\/p>\n\n\n\n<p><strong>\u4f46\u7ef4\u751f\u7d20E\u9664\u4e86\u53ef\u4ee5\u5bfc\u81f4\u80ba\u764c\u8fc7\u5feb\u589e\u957f\u5916\uff0c\u8fd8\u4f1a\u4f7f\u7537\u6027\u60a3\u524d\u5217\u817a\u764c\u7684\u98ce\u9669\u589e\u52a0\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720-1024x683.webp\" alt=\"\" class=\"wp-image-3060\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720-1024x683.webp 1024w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720-300x200.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720-768x512.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720-585x390.webp 585w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720-263x175.webp 263w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/25E2AF2E8B613FEEDEC800316043F4D2783EC576_size1399_w1080_h720.webp 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>2011\u5e74\uff0c\u7f8e\u56fd\u7814\u7a76\u4eba\u5458\u53d1\u8868\u5728\u300a\u7f8e\u56fd\u533b\u5b66\u4f1a\u300b\u671f\u520a\u4e0a\u7684\u4e00\u9879\u62a5\u544a\u6307\u51fa\uff0c\u7ecf\u5e38\u670d\u7528\u7ef4\u751f\u7d20E\u53ef\u80fd\u4f1a\u4f7f\u7537\u6027\u60a3\u524d\u5217\u817a\u764c\u7684\u98ce\u9669\u589e\u52a017%\u3002<\/p>\n\n\n\n<p>\u5f53\u65f6\u8fd9\u4e2a\u5b9e\u9a8c\u7684\u8fc7\u7a0b\u662f\uff0c\u7814\u7a76\u4eba\u5458\u57282001\u5e74\u968f\u673a\u5bf935000\u4eba\u5c55\u5f00\u4e86\u201c\u7852\u4e0e\u7ef4\u751f\u7d20\u764c\u75c7\u9884\u9632\u201d\u9879\u76ee\uff0c\u4ed6\u4eec\u628a\u53c2\u4e0e\u8005\u5206\u62104\u7ec4\uff0c\u4e00\u7ec4\u4eba\u670d\u7528\u7852\uff0c\u4e00\u7ec4\u4eba\u670d\u7528\u7ef4\u751f\u7d20E\uff08\u6bcf400\u5355\u4f4d\uff09\uff0c\u4e00\u7ec4\u4eba\u670d\u7528\u7852\u548c\u7ef4\u751f\u7d20E\uff0c\u6700\u540e\u4e00\u7ec4\u4eba\u670d\u7528\u5b89\u6170\u5242\u3002\u8bd5\u9a8c\u7ed3\u679c\u663e\u793a\uff0c\u670d\u7528\u7ef4\u751f\u7d20E\u7ec4\u6709620\u4eba\u60a3\u4e0a\u524d\u5217\u817a\u764c\uff1b\u670d\u7528\u7852\u548c\u7ef4\u751f\u7d20E\u7ec4\uff0c\u6709555\u4eba\u60a3\u524d\u5217\u817a\u764c\uff1b\u53ea\u670d\u7528\u7852\u7ec4\uff0c\u6709575\u4eba\u60a3\u764c\uff1b\u670d\u7528\u5b89\u6170\u5242\u7ec4\uff0c\u6709529\u4eba\u60a3\u764c\u3002\u7ed3\u8bba\u662f\uff0c\u8ddf\u8e2a10\u5e74\u540e\u53d1\u73b0\uff0c\u4e0e\u670d\u7528\u7852\u8865\u5145\u5242\u6216\u5b89\u6170\u5242\u7684\u7537\u6027\u76f8\u6bd4\uff0c\u90a3\u4e9b\u53ea\u670d\u7528\u7ef4\u751f\u7d20E\u7ec4\u7684\u7537\u6027\uff0c\u60a3\u524d\u5217\u817a\u764c\u7684\u98ce\u9669\u8f83\u9ad8\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"960\" height=\"720\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/70FA4618D9B2E006CF23265D303BC94C6E6C7D80_size311_w960_h720.webp\" alt=\"\" class=\"wp-image-3061\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/70FA4618D9B2E006CF23265D303BC94C6E6C7D80_size311_w960_h720.webp 960w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/70FA4618D9B2E006CF23265D303BC94C6E6C7D80_size311_w960_h720-300x225.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/70FA4618D9B2E006CF23265D303BC94C6E6C7D80_size311_w960_h720-768x576.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/70FA4618D9B2E006CF23265D303BC94C6E6C7D80_size311_w960_h720-585x439.webp 585w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/><\/figure>\n\n\n\n<p>\u8fd9\u4e2a\u5b9e\u9a8c\u906d\u5230\u4e86\u4e00\u4e9b\u8d28\u7591\uff0c\u4e3b\u8981\u5c31\u662f\u53c2\u4e0e\u5b9e\u9a8c\u5bf9\u8c61\u81ea\u8eab\u7684\u5fae\u91cf\u5143\u7d20\u72b6\u51b5\u548c10\u5e74\u8fc7\u7a0b\u4e2d\u4e0d\u540c\u8eab\u4f53\u72b6\u51b5\uff0c\u53ef\u80fd\u5bfc\u81f4\u7ed3\u679c\u7684\u504f\u5dee\u3002\u6b64\u524d\u6709\u7814\u7a76\u663e\u793a\uff0c\u6444\u53d6\u7852\u7684\u7537\u6027\uff0c\u7f79\u60a3\u524d\u5217\u817a\u764c\u7684\u51e0\u7387\u6bd4\u5176\u4ed6\u7537\u6027\u4f4e\u4e86\u4e00\u534a\uff0c\u90a3\u4e48\u4e3a\u4ec0\u4e48\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\u540c\u65f6\u6444\u53d6\u7852\u548c\u7ef4\u751f\u7d20E\u7684\u4eba\u60a3\u75c5\u6570\u91cf\u6bd4\u5355\u72ec\u6444\u5165\u7ef4\u751f\u7d20E\u7684\u8fd8\u5c11\u5462\uff1f<\/p>\n\n\n\n<p><strong>\u5c3d\u7ba1\u5982\u6b64\uff0c\u7f8e\u56fd\u9884\u9632\u670d\u52a1\u5de5\u4f5c\u7ec4\uff08U.S. Preventative Services Task Force\uff09\u4ecd\u7136\u5efa\u8bae\u907f\u514d\u8865\u5145\u03b2-\u80e1\u841d\u535c\u7d20\u548c\u7ef4\u751f\u7d20E\uff0c\u7406\u7531\u662f\u5b83\u4eec\u4f1a\u589e\u52a0\u60a3\u67d0\u4e9b\u7c7b\u578b\u764c\u75c7\u548c\u6b7b\u4ea1\u7684\u98ce\u9669\uff0c\u4f46\u53c8\u8bf4\uff0c\u8fd9\u4e9b\u5efa\u8bae\u4ec5\u9002\u7528\u4e8e\u5728\u9884\u9632\u5fc3\u8840\u7ba1\u75be\u75c5\u548c\u764c\u75c7\u65b9\u9762\u6ca1\u6709\u7279\u6b8a\u8425\u517b\u9700\u6c42\u7684\u5065\u5eb7\u6210\u5e74\u4eba\u3002<\/strong><\/p>\n\n\n\n<p>\u4e0e\u8fd9\u79cd\u5145\u6ee1\u9650\u5b9a\u4fee\u9970\u8bcd\u7684\u7ed3\u8bba\u7c7b\u4f3c\uff0c2019\u5e74\u7f8e\u56fd\u300a\u56fd\u5bb6\u764c\u75c7\u7814\u7a76\u6240\u6742\u5fd7\u300b\u53d1\u8868\u7684\u4e00\u7bc7\u6587\u7ae0\u8bf4\uff0c\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u5e03\u91cc\u683c\u59c6\u5987\u5973\u533b\u9662\u7684Kathryn T. Hall\u535a\u58eb\u53ca\u5176\u56e2\u961f\u901a\u8fc7\u4e00\u987920\u5e74\u6d89\u53ca5\u4e07\u4eba\u7684\u7814\u7a76\u53d1\u73b0\uff0c\u6709\u7279\u5b9a\u57fa\u56e0\u7a81\u53d8\u8865\u5145\u7ef4\u751f\u7d20E\u624d\u80fd\u964d\u4f4e\u764c\u75c7\u98ce\u9669\uff0c\u5426\u5219\u4e0d\u964d\u53cd\u5347\uff0c\u800c\u67d0\u4e9b\u57fa\u56e0\u578b\u7684\u75c5\u4eba\u5728\u8865\u5145\u7ef4\u751f\u7d20E\u540e\uff0c\u4e73\u817a\u764c\u3001\u80ba\u764c\u3001\u5b50\u5bab\u764c\u548c\u6dcb\u5df4\u7624\u767d\u8840\u75c5\u7684\u53d1\u75c5\u98ce\u9669\u90fd\u4e0a\u5347\u4e86\u3002<\/p>\n\n\n\n<p>2015\u5e74\uff0c\u7f8e\u56fd\u53e6\u4e00\u9879\u7814\u7a76\uff0c\u53f7\u79f0\u9009\u62e9\u4e86\u4e09\u79cd\u6700\u666e\u904d\u7684\u975e\u5904\u65b9\u7ef4\u751f\u7d20\u2014\u2014\u7ef4\u751f\u7d20E\u3001\u03b2-\u80e1\u841d\u535c\u7d20\u548c\u53f6\u9178\u7684\u836f\u7247\u6216\u8865\u5145\u5242\u5c55\u5f00\u7814\u7a76\uff0c\u7ed3\u8bba\u662f\u6bcf\u5929\u6444\u5165\u7684\u7ef4\u751f\u7d20\u8865\u5145\u5242\u5343\u4e07\u4e0d\u8981\u8fc7\u91cf\uff0c\u201c\u6211\u4eec\u5bf9\u6570\u5343\u540d\u957f\u671f\u5403\u7ef4\u751f\u7d20\u8865\u5145\u5242\u7684\u4eba\u8fdb\u884c\u4e86\u7814\u7a76\uff0c\u7ed3\u679c\u53d1\u73b0\u90a3\u4e9b\u8865\u5145\u5242\u5bf9\u4ed6\u4eec\u7684\u5065\u5eb7\u5e76\u6ca1\u6709\u4ec0\u4e48\u76ca\u5904\u3002\u4e8b\u5b9e\u4e0a\uff0c\u5f88\u591a\u4eba\u867d\u7136\u8865\u5145\u4e86\u7ef4\u751f\u7d20\uff0c\u4f46\u60a3\u764c\u75c7\u7684\u6982\u7387\u5374\u589e\u52a0\u4e86\u201d\u3002<\/p>\n\n\n\n<p><strong>\u4f46\u95ee\u9898\u662f\u5982\u4f55\u5b9a\u4e49\u201c\u8fc7\u91cf\u201d\u6216\u201c\u7279\u6b8a\u9700\u6c42\u201d\uff0c\u8fd9\u5e76\u6ca1\u6709\u666e\u904d\u6807\u51c6\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"502\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/D90CD39FFCD95ED2C64351AF2954BB331329ADC4_size297_w1080_h529-1024x502.webp\" alt=\"\" class=\"wp-image-3062\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/D90CD39FFCD95ED2C64351AF2954BB331329ADC4_size297_w1080_h529-1024x502.webp 1024w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/D90CD39FFCD95ED2C64351AF2954BB331329ADC4_size297_w1080_h529-300x147.webp 300w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/D90CD39FFCD95ED2C64351AF2954BB331329ADC4_size297_w1080_h529-768x376.webp 768w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/D90CD39FFCD95ED2C64351AF2954BB331329ADC4_size297_w1080_h529-585x287.webp 585w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/D90CD39FFCD95ED2C64351AF2954BB331329ADC4_size297_w1080_h529.webp 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>\u258e<\/strong>NR\u4e0eNMN\uff08\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\uff09\u5747\u662f\u5f53\u4e0b\u5927\u706b\u7684\u6240\u8c13\u957f\u5bff\u836f\u7269\u3002\u4f462022\u5e7411\u6708\uff0c\u5bc6\u6b47\u6839\u5927\u5b66\u5316\u5b66\u7cfb\u526f\u6559\u6388\u57c3\u7433\u5a1c\u00b7\u5188\u9886\u5bfc\u7684\u56fd\u9645\u56e2\u961f\u5728Biosensors and Bioelectronics\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u7814\u7a76\uff0c\u9898\u4e3a\u201cA bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD+ metabolism\u201d\u3002\u7ed3\u8bba\u662f\uff1a\u9ad8\u6c34\u5e73\u7684\u70df\u9170\u80fa\u6838\u7cd6\u82f7\uff08nicotinamide riboside\uff0c\u7b80\u79f0NR\uff0c\u4e00\u79cd\u7ef4\u751f\u7d20B3\uff09\u4e0d\u4ec5\u4f1a\u589e\u52a0\u60a3\u4e09\u9634\u6027\u4e73\u817a\u764c\u7684\u98ce\u9669\uff0c\u8fd8\u4f1a\u5bfc\u81f4\u764c\u75c7\u8f6c\u79fb\u6216\u6269\u6563\u5230\u5927\u8111\u3002<\/p>\n\n\n\n<p><strong>\u764c\u75c7\u60a3\u8005\u5e94\u8c28\u614e\u4f7f\u7528\u7ef4\u751f\u7d20\uff01\u666e\u901a\u4eba\u8fd8\u6562\u670d\u7528\u7ef4\u751f\u7d20\u5417\uff1f<\/strong><\/p>\n\n\n\n<p><strong>\u90a3\u4e48\uff0c\u6d88\u8d39\u8005\u8d2d\u4e70\u7ef4\u751f\u7d20\u8865\u5145\u5242\u6709\u6ca1\u6709\u7528\uff0c\u6216\u8005\u4f1a\u4e0d\u4f1a\u81f4\u764c\uff1f<\/strong><\/p>\n\n\n\n<p>\u8fd9\u4f3c\u4e4e\u662f\u4e00\u4e2a\u4e0e\u5177\u4f53\u751f\u5316\u9886\u57df\u8bba\u6587\u7814\u7a76\u7ed3\u679c\u66f4\u4e0d\u6cbe\u8fb9\u7684\u4e8b\u60c5\u3002\u7814\u7a76\u8868\u660e\uff0c\u4f5c\u4e3a\u8865\u5145\u5242\u670d\u7528\u7684\u8425\u517b\u7d20\u53ef\u80fd\u4e0d\u4f1a\u4ea7\u751f\u4e0e\u98df\u7269\u4e2d\u6444\u5165\u76f8\u540c\u7684\u6548\u679c\u3002\u8fd9\u662f\u56e0\u4e3a\u8425\u517b\u7d20\u7684\u4f5c\u7528\u53ef\u80fd\u662f\u7531\u4e8e\u4e0d\u540c\u98df\u7269\u5316\u5408\u7269\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u9020\u6210\u7684\uff0c\u800c\u5f53\u8425\u517b\u7d20\u5728\u8865\u5145\u5242\u4e2d\u5206\u79bb\u65f6\uff0c\u8fd9\u79cd\u76f8\u4e92\u4f5c\u7528\u4e0d\u4f1a\u53d1\u751f\uff0c\u6216\u4ea7\u751f\u76f8\u53cd\u4f5c\u7528\u3002<\/p>\n\n\n\n<p>\u03b2-\u80e1\u841d\u535c\u7d20\u662f\u852c\u83dc\u548c\u6c34\u679c\u4e2d\u53d1\u73b0\u7684\u6a59\u8272\u8272\u7d20\uff0c\u5728\u4f53\u5185\u8f6c\u5316\u4e3a\u7ef4\u751f\u7d20A\u3002\u6df1\u7eff\u53f6\u852c\u83dc\u3001\u80e1\u841d\u535c\u3001\u7ea2\u85af\u3001\u8292\u679c\u548c\u674f\u5e72\u7b49\u98df\u7269\u4e2d\u7684\u03b2-\u80e1\u841d\u535c\u7d20\u542b\u91cf\u6b63\u5e38\uff0c\u53ef\u80fd\u6709\u52a9\u4e8e\u9884\u9632\u764c\u75c7\u3002\u7136\u800c\uff0c\u670d\u7528\u9ad8\u5242\u91cf\u03b2-\u80e1\u841d\u535c\u7d20\u8865\u5145\u5242\uff08\u6bcf\u592920\u6beb\u514b\u6216\u66f4\u591a\uff09\u662f\u5438\u70df\u6216\u4e60\u60ef\u5438\u70df\u7684\u4eba\u60a3\u80ba\u764c\u7684\u4e00\u4e2a\u539f\u56e0\u3002<strong>\u6240\u4ee5\uff0c\u7f8e\u56fd\u764c\u75c7\u59d4\u5458\u4f1a\u5efa\u8bae\u4eba\u4eec\u907f\u514d\u670d\u7528\u9ad8\u5242\u91cf\uff0c\u5373\u5927\u4e8e20\u6beb\u514b\u03b2-\u80e1\u841d\u535c\u7d20\u8865\u5145\u5242\uff0c\u5c24\u5176\u662f\u5438\u70df\u7684\u4eba\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"400\" src=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/2129AD0F83C8632EBE6C0CF573AC279949AC5326_size29_w500_h400.webp\" alt=\"\" class=\"wp-image-3063\" srcset=\"https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/2129AD0F83C8632EBE6C0CF573AC279949AC5326_size29_w500_h400.webp 500w, https:\/\/newswz.com\/wp-content\/uploads\/2023\/12\/2129AD0F83C8632EBE6C0CF573AC279949AC5326_size29_w500_h400-300x240.webp 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" 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